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Well then, at what creatinine level will dialysis be advised? Can we avoid dialysis treatment? Actually, whether you should start dialysis depends on your own illness conditions. Generally speaking, with the decrease of kidney function, creatinine level will become higher and higher. Usually, dialysis is suggested when serum creatinine is as high as 5, but not everyone will definitely start dialysis at that time. For some kidney failure patients, they do not start dialysis until their life is really threatened. Besides, people with kidney failure caused by Diabetic Nephropathy usually start dialysis earlier, and they may be asked to do dialysis when their creatinine increases 4.5. After all, different people have different tolerant ability to toxins and wastes.